hrp0097p1-593 | Thyroid | ESPE2023

Congenital malformations in permanent and transient congenital hypothyroidism – prevalence and etiology

Ouarezki Yasmina , Shepherd Sheila , Jones Jeremy , Abubaker Alghanay A , Smith Sarah , Shaikh Guftar , Donaldson Malcolm

Background: An increased prevalence of extra-thyroidal congenital malformations in infants with congenital hypothyroidism (CH) is well established. However, accurate estimation of prevalence figures requires careful distinction between permanent and transient CH. Moreover, the mechanisms resulting in congenital malformations are not well understood.Study aim: To estimate the prevalence of cardiac, extra-cardiac and/or sy...